王广

组织学与胚胎学 教授


个人简介


职称:教授

学科专业:组织学与胚胎学

研究方向:发育微环境变化与先天性疾病以及子代疾病易感性的研究

行政职务:太阳成集团tyc539官网副经理

电子邮箱:t_wangguang@jnu.edu.cn

个人介绍:

王广,太阳成集团tyc539官网教授、博士生导师、副经理。兼任中国解剖学会组织学与胚胎学分会委员副主任委员,中国解剖学会青年工作委员会副主任委员,广东省解剖学会副秘书长等社会兼职,入选广东省青年科学家协会会员,获得广州市珠江科技新星、中国解剖学会“青年解剖科学家奖”等荣誉。

迄今,主持国家自然科学基金4项,其他省部级以上项目6项。在SCI杂志如BMC Med.,Redox Bio.,Pharmacol Res.,Phytomedicine,Environ Int.,Cell Death Dis.,Nephrol Dial Transplant.,FASEB J.,Am J Pathol.等优秀期刊发表(共)第一/通讯SCI论文60余篇,Google学术引用次数1700余次,H-Index>26,获得发明专利授权7项(5项第一发明人),任《中国组织化学与细胞化学杂志》常务编委、《中国病理生理杂志》编委等。

作为负责人建设认定省级虚拟仿真实验教学中心1项,参编科学出版社(副主编)、华中科技大学出版社(主编)“十四五”规划教材《组织学与胚胎学》,人民卫生出版社第十轮规划教材《组织学与胚胎学》实验指导等教材7部,参与的《组织学与胚胎学》获得广东省一流本科课程-线上线下混合式一流课程、广东省一流本科课程-线上一流课程等认证。指导本科生获得 “挑战杯”竞赛国赛二等奖、全国大学生创新创业年会“优秀论文”、“互联网+”国赛银奖等国赛荣誉6项。个人曾获太阳城集团优秀共产党员、本科教学董事长奖-青年教师教学综合奖、太阳城集团先进工会工作者等奖励。


学习经历


2010.09-2013.06,太阳城集团医学院病理学与病理生理学,博士,导师:杨雪松

2007.09-2010.06,佳木斯大学医学院免疫学,硕士,导师:马淑霞,杨景云

2002.09-2006.07,济南大学化学化工学院生物技术,学士 


工作经历


2023/12至今,太阳城集团,太阳成集团tyc539官网,副经理

2022/03至今,太阳城集团,太阳成集团tyc539官网基础医学实验教学中心党支部,书记

2021/10至今,太阳城集团,基础医学院组织学与胚胎学系,教授

2021/05- 2022/12,太阳城集团,校团委,副书记(挂职)

2021/01- 2024/02,太阳城集团,基础医学实验教学中心,主任;基础医学形态学实验教学中心,主任(兼);组织学与胚胎学系,主任(兼)

2017/09- 2020/12,太阳城集团,基础医学院形态学实验教学中心,主任

2015/10- 2021/09,太阳城集团,基础医学院组织学与胚胎学系,副教授

2015/07- 2015/08,University of East Anglia,School of Biological Sciences,访问学者

2013/07- 2015/09, 太阳城集团,医学院组织学与胚胎学系,讲师


主要论文


教学论文

[1]Wang G#, Ma XY#, Cheng X#, Luo CH , Wang H, Xu X, Lee K K, Yang X*.The effects of long-term extracurricular scientific research on the medical students: insight from Jinan University Medical School. Biochem Mol Biol Educ. 2021 Mar 8. doi: 10.1002/bmb.21499. Online ahead of print. (IF: 1.16,第一作者)

科研论文

[1]Guang Wang#* , Ran Zhao# , Xinxia Zhang#, Ying Zheng# , Feiling Xie , Yu Jiang , Guohua Lv , Denglu Long , Chengyang Sun , Yongping Bao , Shuangyu Qi , Xinyue Liu , Qihao Zhang , Xuesong Yang*. EGFR/MAPK signaling pathway acts as a potential therapeutic target for sulforaphane-rescued heart tube malformation induced by various concentrations of PhIP exposure. Phytomedicine. 2024 Jan:123:155270.. doi: 10.1016/j.phymed.2023.155270. (IF: 7.9JCR 1Top期刊, 共同第一和共同通讯作者)

[2]Xiaotan Zhang#, Guang Wang#*, Ming Li, Yunjin Li, Xin Luo, Yvonne Liu, Xiaoli Zhang, Johann-Georg Hocher, Bernhard K. Krämer, Berthold Hocher*, Xuesong Yang*. Both partial inactivation as well as activation of NF-κB signaling lead to hypertension and chronic kidney disease. Nephrol Dial Transplant. 2024.  (IF: 6.1, Top期刊, 共同第一和共同通讯作者)

[3]Jia-Qi Lu#, Zhi-Yan Luo#, Chengyang Sun, Si-Miao Wang, Dixiang Sun, Ruo-Jing Huang, Xuesong Yang*, Yong Ding*, Guang Wang*. Baicalin administration could rescue high glucose-induced craniofacial skeleton malformation by regulating neural crest development. Front Pharmacol. 2024.  (IF: 5.6, 共同通讯作者 )

[4]Jingyun Wang#, Ping Zhang#, Mengyuan Liu#, Zhengrui Huang, Xiaofeng Yang , Yuzhen Ding, Jia Liu, Xin Cheng, Shujie Xu, Meiyao He, Fengxiang Zhang, Guang Wang*, Ruiman Li*, Xuesong Yang*. Alpha-2-macroglobulin is involved in the occurrence of early-onset pre-eclampsia via its negative impact on uterine spiral artery remodeling and placental angiogenesis. BMC Med. 2023 Mar 9;21(1):90. doi: 10.1186/s12916-023-02807-9. (IF: 9.3JCR 1Top期刊, 共同通讯作者)

[5]Mei-yao He, Ping Zhang, Nannan Shi, Tingting Li, Jingyun Wang, Longkai He, Zefeng Liang, Linliang Song, Guang Wang*, Xuesong Yang*. Nrf2 is involved in hyperglycemia-induced abnormal lung development through both antioxidation-dependent and antioxidation-independent activation. Am J Respir Cell Mol Biol. 2023Feb 13. doi: 10.1165/rcmb.2022-0345OC.(IF:6.4JCR 1Top期刊, 封面文章, 共同通讯作者)

[6]Yao Shen#, Yipiao Wang#, Xin Cheng, Xuesong Yang*, Guang Wang*. Autophagy regulation combined with stem cell therapy for treatment of spinal cord injury. Neural Regen Res. 2023 August 18(8):1629-1636, (IF:6.1,通讯作者)

[7]Meiting Shi, Xiaofeng Yang, Lu Sun, Yuzhen Ding, Zhengrui Huang, Ping Zhang, Xuesong Yang*, Ruiman Li*, Guang Wang*. Comparison of different modified operations in the reduced uteroplacental perfusion pressure rat model of preeclampsia. J Reprod Immunol. 2023 Jan 23;156:103815. (IF:3.6,通讯作者)

[8]Xiaofeng Yang#, Yuzhen Ding#, Lu Sun, Meiting Shi, Ping Zhang, Zhengrui Huang, Jingyun Wang, Andong He, Jian Wang, Jiachun Wei, Mengyuan Liu, Jia Liu, Guang Wang*, Xuesong Yang*, Ruiman Li*. Ferritin light chain deficiency-induced ferroptosis is involved in preeclampsia pathophysiology by disturbing uterine spiral artery remodeling. Redox Biol. 2022. Nov 24;58:102555. (IF: 11.4JCR 1Top期刊, 共同通讯作者)

[9]Mengwei Wang#, Ping Zhang#, Zeyu Li, Yu Yan, Xin Cheng, Guang Wang*, Xuesong Yang*. Different cellular mechanisms from low- and high-dose zinc oxide nanoparticles-induced heart tube malformation during embryogenesis. Nanotoxicology. 2022 Sep 22;1-17.doi: 10.1080/17435390.2022.2124130. (IF: 5.0Top期刊, 共同通讯作者)

[10]Haiyang Li#, Denglu Long#, Guohua Lv#, Xin Cheng, Guang Wang*, Xuesong Yang*.The double-edged sword role of TGF-β signaling pathway between intrauterine inflammation and cranial neural crest development. FASEB J. 2022 Jan;36(1):e22113. doi: 10.1096/fj.202101343R. (IF: 4.8Top期刊,共通讯作者)

[11]Xin Luo, Junjie Xu, Ran Zhao, Jiajia Qin, Xiaoyu Wang, Yu Yan, Li-jing Wang, Guang Wang*, Xuesong Yang*. The Role of Inactivated NF-κB in Premature Ovarian Failure. Am J Pathol. 2022 March;192(3):468-483. doi: 10.1016/j.ajpath.2021.12.005.(IF: 6.0Top期刊,共同通讯作者)

[12]Tonghua Zhang, Jianxin Liang,Denglu Long, Min Ma, Li-guo Chen, Da-xiang Lu, Xiaohua Jiang, Xuesong Yang, Guang Wang*. Tocolysis Effects of Traditional Chinese Medicine and Their Effective Components.  World Journal of Traditional Chinese Medicine. 2022. April8(2)188-198. Doi: 10.4103/wjtcm.wjtcm_30_21 (IF: 4.4通讯作者)

[13]Jingyun Wang#, Yun Wang#, Mei-yao He#, Yi-xiao Li#, Xin Cheng, Xuesong Yang*, Rui-man Li*, Guang Wang*. Maternal and infant outcomes during the COVID-19 pandemic: a retrospective study in Guangzhou, China. Reprod Biol Endocrinol. 2021 Aug 17;19(1):126. doi: 10.1186/s12958-021-00807-z.. (IF: 4.982共同通讯作者)

[14]Andong He#, Jingyun Wang#, Xiaofeng Yang, Jia Liu, Xuesong Yang, Guang Wang*, Ruiman Li*. Screening of differentially expressed proteins in placentas from patients with late-onset preeclampsia. Proteomics Clin Appl. 2021 Oct 27;e2100053. doi: 10.1002/prca.202100053. (IF: 3.603共同通讯作者)

[15]Jia-hui Nie, Yao Shen, Mohamed Roshdy, Xin Cheng, Guang Wang*, XuesongYang*. Polystyrene nanoplastics exposure caused defective neural tube morphogenesis through caveolae-mediated endocytosis and faulty apoptosis. Nanotoxicology. 2021. Sep;15(7):885-904. doi: 10.1080/17435390.2021.1930228 (IF: 5.881Top期刊共同通讯作者)

[16]Denglu Long#, Meng Liu#, Haiyang Li, Jinhuan Song, Xiaohua Jiang, GuangWang* , Xuesong Yang*. Dysbacteriosis induces abnormal neurogenesis via LPS in a pathway requiring NF-κB/IL-6. Pharmacol Res. 2021 Mar 10;167:105543.  doi: 10.1016/j.phrs.2021.105543(IF: 10.334, Top期刊, 共同通讯作者)

[17]Guang Wang#, Yu-xuan Hu#, Mei-yao He#, Yun-hai Xie, Wei Su, Deng-lu Long, Ran Zhao, Jing-yun Wang, Chen-yang Dai, Haiyang Li, Zhen-peng Si, Xin Cheng, Rui-man Li, Zhi-jie Li, Xuesong Yang*. Gut-lung dysbiosis accompanied by diabetes mellitus leads to pulmonary fibrotic change through the NF-κB signaling pathway. Am J Pathol. 2021 May;191(5):838-856. doi: 10.1016/j.ajpath.2021.02.019. Epub 2021 Mar 9.  (IF:5.770Top期刊,第一作者)

[18]Nian Wu# , Yingshi Li# , Xiangyue He#, Jiayi Lin# , Denglu Long, Xin Cheng, Beate Brand-Saberi, Guang Wang* , Xuesong Yang*  Retinoic acid signaling plays a crucial role in excessive caffeine intake-disturbed apoptosis and differentiation of myogenic progenitors. Front Cell Dev Biol. 09 March 2021. doi: 10.3389/fcell.2021.586767  (IF:6.081共通讯作者)

[19]ZhangP#, LiT#, Liu C #, SindiM, ChengX, QiS, LiuX, YanY, Bao Y, BrandSaberiB, Yang W,WangG*, Yang X*. Nano-sulforaphane attenuates PhIP-induced early abnormal embryonic neuro-development. Ann Anat. 2021 Jan;233:151617 doi: 10.1016/j.aanat.2020.151617 (IF:2.976,Top期刊共通讯作者)

[20]Yu Yan#, Guang Wang#, Xin Luo#, Ping Zhang, Shuang Peng, Xin Cheng, Mengwei Wang, Xuesong Yang*. Endoplasmic reticulum stress-related calcium imbalance plays an important role on Zinc oxide nanoparticles-induced failure of neural tube closure during embryogenesis. Environ Int. 2021. 152: 106495. https://doi.org/10.1016/j.envint.2021.106495  (IF: 13.352, A1 一区,Top期刊,共第一作者)

[21]Zhang XT#; Wang G#; Ye LF; Pu Y; Li RT; Liang J; Wang L; Lee K K; Yang X*. Baicalin reversal of DNA hypermethylation-associated Klotho suppression ameliorates renal injury in type 1 diabetic mouse model. Cell Cycle. 2020. Nov 16;1-19. doi: 10.1080/15384101.2020.1843815. (IF:4.534,共第一作者)

[22]Yan Y #, Wang G #, Huang J, Zhang Y, Cheng X, Chuai M, Brand-Saberi B, Chen G, Jiang X, Yang X. Zinc oxide Nanoparticles exposure-induced oxidative stress restricts cranial neural crest development during chicken embryogenesis. Ecotoxicol Environ Saf. 2020. May;194:110415. doi: 10.1016/j.ecoenv.2020.110415. (IF:6.291Top期刊共第一作者)

[23]Jinhuan Song #, Chaojie Wang #, Denglu Long, Ziguang Li, Lingsen You, Beate Brand-Saberi, Guang Wang*, Xuesong Yang*. Dysbacteriosis-induced LPS elevation disturbs the development of muscle progenitor cells by interfering with retinoic acid signaling. FASEB J. 2020 May;34(5):6837-6853. doi: 10.1096/fj.201902965R.(IF: 5.191Top期刊,共通讯作者)

[24]Wang G#, Lu JQ#, Ding Y#, Zhang TH, Song JH , Long DL, Liang JX, Si ZP, Qi GL, Jiang XH, Yang X*. Baicalin rescues hyperglycemia-induced neural tube defects via targeting on retinoic acid signaling. Am J Transl Res 2020;12(7):3311-3328. (IF: 4.06,第一作者)

[25]Li YX#,  Long DL#,  Liu J,  Qiu D, Wang JY, Cheng X, Yang X, Li RM*, Wang G*.  Gestational diabetes mellitus in women increased the risk of neonatal infection via inflammation and autophagy in the placenta. Medicine (Baltimore) 2020 Oct 2; 99(40): e22152  (IF: 1.889,共通讯作者)

[26]Xie J#, Jin Y#, Wang G*. The role of SCF ubiquitin-ligase complex at the beginning of life. Reprod Biol Endocrinol. 2019 Nov 28;17(1):101. doi: 10.1186/s12958-019-0547-y.  (IF: 3.235,通讯作者)

[27]Wang G# , Jiang LM#, Tan BY #, Li PZ , Zhang PL , Zhang Y , Cheng X , Ma Z , Li ZJ , Brand-Saberi B , Yang X*. Cell survival controlled by lens-derived Sema3A /Nrp1 is vital on caffeine-suppressed corneal innervation during chick organogenesis. J Cell Physiol. 2019 Jun;234(6):9826-9838. doi: 10.1002/jcp.27671. (IF:5.546,第一作者)

[28]Si ZP#; Wang G#; Han SS; Jin Y; Hu YX; He MY; Brand-Saberi B; Yang X* , Liu GS*. CNTF and Nrf2 Are Coordinately Involved in Regulating Self-Renewal and Differentiation of Neural Stem Cell during Embryonic Development. iScience. 2019 Sep 27;19:303-315. doi: 10.1016/j.isci.2019.07.038. (IF: 4.447,共第一作者)

[29]Xu J #, Wang G #, Luo X, Wang LJ, Bao Y, Yang X*. Role of nuclear factor-κB pathway in the transition of mouse secondary follicles to antral follicles. J Cell Physiol. 2019 Dec;234(12):22565-22580. doi: 10.1002/jcp.28822. (IF: 5.546,共第一作者)

[30]Wang G#, Li PZ#, Zhang SY, Zhong S, Chu C, Zeng SF, Yan Y, Cheng X, Chuai M, Hocher B*, Yang X*. Lipopolysaccharides (LPS) induced angiogenesis during chicken embryogenesis is abolished by combined ETA/ETB receptor blockade. Cell Physiol Biochem. 2018;48(5):2084-2090. doi: 10.1159/000492547. Epub 2018 Aug 10. (IF: 5.5,第一作者)

[31]Wang G#, Liang J#, Gao LR, Si ZP, Zhang XT, Liang G, Yan Y, Li K, Cheng X, Bao Y, Chuai M, Chen LG, Lu DX, Yang X*. Baicalin administration attenuates hyperglycemia-induced malformation of cardiovascular system. Cell Death Dis. 2018 Feb 14;9(2):234. doi: 10.1038/s41419-018-0318-2. (IF:5.959第一作者)

[32]Wang G#, Chen EN#, Liang C#, Liang J, Gao LR, Chuai M, Münsterberg A, Bao Y, Cao L*, Yang X*. Atg7-mediated autophagy is involved in the neural crest cell generation in chick embryo. Mol Neurobiol. 2018 Apr;55(4):3523-3536. doi: 10.1007/s12035-017-0583-6. (IF: 4.586, 第一作者)

[33]Wang G#, Nie JH#, Bao Y*, Yang X*. Sulforaphane rescues ethanol-suppressed angiogenesis through oxidative and endoplasmic reticulum stress in chick embryos. J Agric Food Chem. 2018 Sep 12;66(36):9522-9533. doi: 10.1021/acs.jafc.8b02949.(IF:3.571, A1 一区Top期刊, 第一作者)

[34]Gao LR#, Wang G.#, Zhang J, Li S, Chuai M, Bao Y, Hocher B, Yang X*. High salt-induced excess reactive oxygen species production resulted in heart tube malformation during gastrulation. J Cell Physiol. 2018 Sep;233(9):7120-7133. doi: 10.1002/jcp.26528. (IF:4.522,共第一作者)

[35]Long Y#, Wang G#, Li K, Zhang ZY, Zhang P, Zhang J, Zhang XT, Bao YP, Yang X*, Wang P*. Oxidative Stress and NF-κB signaling are involved in LPS induced pulmonary dysplasia in chick embryos. Cell Cycle. 2018;17(14):1757-1771. doi: 10.1080/15384101.2018.1496743. (IF:3.259, 共第一作者)

[36]He MY#, Wang G#, Han SS#, Li K, Jin Y, Liu M, Si ZP, Wang J, Liu GS*, Yang X*. Negative impact of hyperglycaemia on mouse alveolar development. Cell Cycle. 2018;17(1):80-91. doi: 10.1080/15384101.2017.1403683.  (IF:3.259, 共第一作者)

[37]Zhang P#, Zhong S#, Wang G#, Zhang SY#, Chu C, Zeng S, Yan Y, Cheng X, Bao Y, Hocher B*. Yang X*. N-Acetylcysteine Suppresses LPS-Induced Pathological Angiogenesis. Cell Physiol Biochem. 2018;49(6):2483-2495. doi: 10.1159/000493874.  (IF:5.5, 共第一作者)

[38]Zhang J#, Wang G#, Liu J#, Gao LR, Liu M, Wang CJ, Chuai M, Bao Y, Li G, Li R, Zhang Y, Yang X. Gut microbiota-derived endotoxin enhanced the incidence of cardia bifida during cardiogenesis, J Cell Physiol. 2018 Dec;233(12):9271-9283. doi: 10.1002/jcp.26175 (IF:4.522,共第一作者)

[39]Wang G#, Chen BZ#,Wang CJ, Zhang J, Gao LR, Chuai M,Bao Y, Yang X*. Ethanol exposure leads to disorder of blood island formation in early chick embryo. Reprod Toxicol. 2017 Oct;73:96-104. doi: 10.1016/j.reprotox.2017.08.003. (IF:2.58,第一作者)

[40]Yeung C K#, Wang G#, Yao Y, Liang J, Chung C Y, Chuai M, Lee K K*, Yang X*. BRE modulates granulosa cell death to affect ovarian follicle development and atresia in the mouse. Cell Death Dis. 2017 Mar 23;8(3):e2697. doi: 10.1038/cddis.2017.91. (IF: 5.638, 共第一作者)

[41]Zhang P#, Wang G#, Lin Z#, Wu Y#, Zhang J, Liu M, Chuai M, Lee KK, Yang X*. Alcohol exposure induces chick craniofacial bone defects by negatively affecting cranial neural crest development. Toxicol Lett. 2017 Nov 5;281:53-64. doi: 10.1016/j.toxlet.2017.09.010.  (IF:3.166, 共第一作者)

[42]Gao L R#, Li S# ; Zhang J, Liang C, Chen E N ; Zhang S Y ; Chuai M ; Bao Y; Wang G*, Yang X*. Excess imidacloprid exposure causes the heart tube malformation of chick embryos. J Agric Food Chem. 2016 Nov 30;64(47):9078-9088. (IF:3.154, A1 一区,Top期刊, 通讯作者)

[43]Wang G#, Yeung C K#, Wong W Y, Zhang N, Wei Y F, Zhang J L, Yan Y, Wong C Y, Tang J J, Chuai M, Lee K K, Wang L J , Yang X*. Liver fibrosis can be induced by high salt intake through excess reactive oxygen species (ros) production. J Agric Food Chem. 2016 Feb 24;64(7):1610-7. doi: 10.1021/acs.jafc.5b05897.(IF:3.154, A1 一区,Top期刊, 第一作者)

[44]Wang G. #, Zhong S#, Zhang S.Y. #, Ma Z. L., Chen J. L., Lu W. H., ChengX, ChuaiM, Lee K K, Lu D.X.*, Yang X*. Angiogenesis is repressed by ethanol exposure during chick embryonic development. J Appl Toxicol. 2016 May;36(5):692-701. doi: 10.1002/jat.3201.  (IF:3.159,第一作者)

[45]Wang CJ#, Wang G#, Wang XY, Liu M, Chuai M, Lee KK, He XS, Lu DX, Yang X*. Imidacloprid Exposure Suppresses Neural Crest Cells Generation during Early Chick Embryo Development. J Agric Food Chem. 2016 Jun 15;64(23):4705-15. doi: 10.1021/acs.jafc.6b01478. (IF:3.15, A1 一区,Top期刊, 共第一作者)

[46]Jin Y#, Wang G#, Han SS, He MY, Cheng X, Ma ZL, Wu X, Yang X*, Liu GS*. Effects of oxidative stress on hyperglycaemia-induced brain malformations in a diabetes mouse model. Exp Cell Res. 2016 Sep 10;347(1):201-11. doi: 10.1016/j.yexcr.2016.08.002. (IF:3.55,共第一作者)

[47]He MY#, Wang G#, Han SS, Jin Y, Li H, Wu X, Ma ZL, Cheng X, Tang X, Yang X*, Liu GS*. Nrf2 signaling and autophagy are involved in diabetes mellitus-induced defects in the development of mouse placenta. Open Biol. 2016 Jul;6(7). pii: 160064. doi: 10.1098/rsob.160064.  (IF:3.48,共第一作者)

[48]Liu M#, Wang G#, Zhang SY, Zhong S, Qi GL, Wang CJ, Chuai M, Lee KK, Lu DX, Yang X*. From the Cover: Exposing Imidacloprid Interferes With Neurogenesis Through Impacting on Chick Neural Tube Cell Survival. Toxicol Sci. 2016 Sep;153(1):137-48. doi: 10.1093/toxsci/kfw111.  (IF: 4.08 ,共第一作者,封面文章)

[49]Ma Z. L. #, Wang G.#, Lu W. H.#, Cheng X, Chuai M, Lee K K, Yang X*. Investigating the effect of excess caffeine exposure on placental angiogenesis using chicken “functional” placental blood vessel network. J Appl Toxicol. 2016 Feb;36(2):285-95. doi: 10.1002/jat.3181. (IF: 3.159, 共第一作者)

[50]Wang G. #, Huang W.Q. #, Cui S.D. #, Li S., Wang X.Y., Li Y., Chuai M., Cao L., Li J.C., Lu D.X.*, Yang X*. Autophagy is involved in high glucose-induced heart tube malformation. Cell Cycle. 2015;14(5):772-83. doi: 10.1080/15384101.2014.1000170.(IF:3.952,第一作者)

[51]Wang G. #, Li Y#, Wang X.Y. #, Chuai M., Chan J.Y., Lei J., Münsterberg A., Lee K.K.*, Yang X*. Mis-expression of BRE gene in the developing chick neural tube affects neurulation and somitogenesis. Mol Biol Cell. 2015 Mar 1;26(5):978-92. doi: 10.1091/mbc.E14-06-1144.(IF:4.037, 第一作者)

[52]Wang G#, Yeung C K#, Zhang J L#, Hu X W, Ye Y X, Yang Y X, Li J C, Lee K K, Yang X*, Wang L J*. High salt intake negatively impacts ovarian follicle development. Ann Anat. 2015 Jul;200:79-87. doi: 10.1016/j.aanat.2015.02.009. (IF: 1.308,第一作者)

[53]Wang G. #, Zhang N. #, Wei Y F. #, Jin Y M, Zhang S Y., Cheng X., Ma Z L., Zhao S Z., Chen Y P., Chuai M, Hocher B., Yang X*. The impact of high salt exposure on cardiovascular development in the early chick embryo. J Exp Biol. 2015 Nov;218(Pt 21):3468-77. doi: 10.1242/jeb.129486. (IF: 2.914,第一作者)

[54]Li S#, Wang G#, Gao L R, Lu W H, Wang X Y, Chuai M, K Lee K K, Cao L, Yang X *. Autophagy is involved in ethanol-induced cardia bifida during chick cardiogenesis. Cell Cycle. 2015;14(20):3306-17. doi: 10.1080/15384101.2015.1087621.  (IF:3.952,共第一作者)

[55]Han S#, Wang G#, Jin Y#, Ma Z L, Jia W J, Wu X, Wang X Y , He M Y, Cheng X, Li W J, Yang X *, Liu G S*. Investigating the mechanism of hyperglycemia-induced fetal cardiac hypertrophy. PLoS One. 2015 Sep 29;10(9):e0139141. doi: 10.1371/journal.pone.0139141. eCollection 2015. (IF:3.057共第一作者)

[56]Cheng X #, Luo R #, Wang G#*, Xu C J, Feng X, Yang R H, Ding E, He Y Q, Chuai M, Lee K K, Yang X*. Effects of 2,5-hexanedione on angiogenesis and vasculogenesis in chick embryos. Reprod Toxicol. 2015 Jan;51:79-89. doi: 10.1016/j.reprotox.2014.12.006. (IF: 2.85, 共第一作者&通讯作者)

[57]Jin Y. M. #, Wang G.,# Zhang N., Wei Y. F., Li S., Chen Y. P., Chuai M, Lee H. S., Hocher B., Yang X.*. Changes in the osmolarity of the embryonic microenvironment induce neural tube defects. Mol Reprod Dev. 2015 May;82(5):365-76. doi: 10.1002/mrd.22482. (IF: 2.141,共第一作者)

[58]Lu W.H. #, Wang G.#, Li Y., Li S., Song X.Y., Wang X.Y., Chuai M., Lee K. K., Cao L.*, Yang X*. Autophagy functions on EMT in gastrulation of avian embryo. Cell Cycle. 2014;13(17):2752-64. doi: 10.4161/15384101.2015.945850. (IF: 4.565, 共第一作者)

[59]Ma Z. L. #, Wang G. #, Cheng X. #, Chuai M., Kurihara H., Lee K. K., Yang X*. Excess caffeine exposure impairs eye development during chick embryogenesis. J Cell Mol Med. 2014 Jun;18(6):1134-43. doi: 10.1111/jcmm.12260. (IF:4.014, 共第一作者)

[60]Chen Y. #, Wang G. #, Wang X. Y., Ma Z. L., Chen Y.P., Chuai M., Websky K., Hocher B. *, Yang X*. Effects of high salt-exposure on the development of retina and lens in 5.5-day chick embryo. Cell Physiol Biochem. 2014;34(3):804-17. doi: 10.1159/000363044. (IF:2.875, 共第一作者)

[61]Wang G., Li Y., Wang X. Y., Han Z., Chuai M., Wang L. J., Ho Lee K. K., Geng J. G. *, Yang X*. Slit/Robo1 signaling regulates neural tube development by balancing neuroepithelial cell proliferation and differentiation. Exp Cell Res. 2013 May 1;319(8):1083-93. doi: 10.1016/j.yexcr.2013.02.011. (IF: 3.372,第一作者)

[62]Cheng X. #, Wang G. #, Ma Z. L., Chen Y. Y., Fan J. J., Zhang Z. L., Lee K. K., Luo H. M.*, Yang X*. Exposure to 2,5-hexanedione can induce neural malformations in chick embryos. Neurotoxicology. 2012 Oct;33(5):1239-47. doi: 10.1016/j.neuro.2012.07.005. (IF: 2.652, 共第一作者)

[63]Ma Z. L. #, Qin Y. #, Wang G. #, Li X. D., He R. R., Chuai M., Kurihara H. *, Yang X*. Exploring the caffeine-induced teratogenicity on neurodevelopment using early chick embryo. PLoS One. 2012;7(3):e34278. doi: 10.1371/journal.pone.0034278  (IF: 3.73, 共第一作者)


专利


发明专利

[1]王广,杨雪松,陆大祥,梁健欣,高麟芮,李帅,钟山,张诗瑶。黄芩苷在制备妊娠合并糖尿病胎儿心脏发育保护药物中的应用(ZL201610290853.2)。 (授权公告日2018.05.08)

[2]王广,卢嘉琪,杨雪松,梁健欣,司振鹏。黄芩苷在制备妊娠期糖尿病胎儿神经管畸形药物的应用(ZL201811419142.6),(授权公告日2020.05.08)

[3]王广,杨雪松,暴永平,聂嘉辉。萝卜硫素制备保护孕期饮酒妇女的胎儿血管发育药物应用(ZL201810547828.7),(授权公告日2020.06.16)

[4]王广,杨雪松,张萍,穆斯塔法•辛迪,刘畅,程欣。萝卜硫素或其纳米粒在制备改善孕妇杂环胺摄入导致的胚胎神经系统发育不良药物中的应用。(ZL202010654574.6,授权公告日2022.11.01)

[5]王广,杨雪松,张彤华。白术内酯Ⅰ在制备妊娠合并糖尿病胚胎发育保护药物中的应用。(ZL202111227437.5,授权公告日2023.3.21)

[6]李瑞满,王广,王静云。定量A2M的产品在制备子痫前期诊断工具中的应用。(ZL202110134187.4,授权公告日2022.11.29)

[7]李瑞满,王广,何安东,杨小锋,王静云。定量FTL的产品在制备子痫前期诊断工具中的应用。(ZL202110123211.4,授权公告日2022.11.29) 


学术著作


王广(编委). 组织学与胚胎学实验指导—彩色图谱及微视频. 人民卫生出版社. 2017

王广(编委). 医学形态实验学Ⅱ—组织胚胎学与病理学分册. 科学出版社. 2022

王广(编委). 组织学与胚胎学(第3版). 科学出版社(“十二五”普通高等教育本科国家级规划教材). 2023年

王广(编委). 组织学与胚胎学实验教程. 华中科技大学出版社(普通高等学校“十四五”规划医学实验教学示范中心新形态教材). 2023年

王广(编委). 组织学与胚胎学实验教程. 人民卫生出版社(全国高等学校五年制本科临床医学专业第十轮规划教材第2版). 2024年编写中

王广(主编).组织学与胚胎学. 华中科技大学出版社(高等医学教育课程“十四五”规划基础医学类系列教材). 2024年编写中

王广(副主编). 组织学与胚胎学. 科学出版社(“十四五”普通高等教育本科国家级规划教材). 2024年编写中


获奖及荣誉


[1]王广、吴莎、张鲍欢、谢敏、黄华梅、何文芳、王礼,广东省高校教育数字化转型优秀案例-智慧教室建设案例二等奖,广东省本科高校教育技术指导委员会,2023年4月

[2]王广,优秀学科主任,太阳成集团tyc539官网,2023年3月

[3]程欣、杨雪松、王广、王晓钰,第二届全国高校教师教学创新大赛广东分赛暨广东省高校教师教学创新大赛(正高组)三等奖,2022年5月

[4]杨雪松,王广,全国大学生创新创业年会获优秀指导教师,2021年12月

[5]程欣、杨雪松、王广、吕国华、吴念、王晓钰,组织学与胚胎学,广东省一流本科课程-线上线下混合式一流课程(编号202012029),2020年12月

[6]杨雪松、程欣、李锦新、李晓明、王广、常青,组织学与胚胎学,广东省一流本科课程-线上一流课程(编号202011014),2020年08月

[7]王广,太阳成集团tyc539官网,2021年度优秀科研工作者,2021年12月30日

[8]王广,中共太阳城集团委员会,太阳城集团优秀共产党员,2021年6月29日

[9]王广,太阳城集团工会委员会,先进工会工作者,2021年05月17日

[10]王广,太阳城集团,“暨南双百英才计划”暨南杰青第一层次,2020年10月

[11]程欣,王广,吴念,杨雪松,吕国华,王晓钰,六融合助力主场云端课堂--太阳城集团基础医学院《组织学与胚胎学》线上教学案例实施,广东省本科高校在线开放课程指导委员会,疫情阶段在线教学优秀案例(第二批-教师或课程类案例(二等奖),2020年4月8日

[12]王广,中共太阳城集团基础医学院委员会,2019年度优秀党员。2020年1月

[13]王广,青年解剖科学家奖,中国解剖学会,2019年8月

[14]杨雪松,程欣,卢晓晔,王广,夏潮涌,常青,太阳城集团,创建“六融合,三递进”课程育人模式,培养具有卓越创新能力的医学人才,太阳城集团教学成果一等奖。2019年5月

[15]王广,太阳城集团基础医学院,2018年度优秀管理工作者。2019年1月

[16]王广,太阳城集团基础医学院,“德仁杯”教学竞赛三等奖。2018年5月24日

[17]王广,太阳城集团优秀本科生班主任。2017年9月

[18]王广,广州市科技创新委员会,珠江科技新星。2017年5月3日


学术兼职


2022年 中国解剖学会组织学与胚胎学分会   副主任委员

2022年 中国解剖学会青年工作委员会       副主任委员

2022年 中国解剖学会医学发育生物学分会   常务委员

2023年 中国生理学会生殖科学专委会       委员

2023年 广东省医学会生殖免疫与优生学分会 委员

2021年 广东省解剖学会   副秘书长兼理事