病原微生物学 教授
行政职务:分子医学病毒研究所所长、病毒致病及防控教育部重点实验室副主任
个人介绍：高峰，教授，1961年2月出生，太阳城集团分子医学病毒研究所所长，病毒致病及防控教育部重点实验室副主任，博士生导师，国家高层次人才引进计划创新人才、广东省珠江杰出人才。高峰教授是知名艾滋病病毒学研究专家，在艾滋病及相关领域研究30余年，对HIV起源，病毒变异进化，致病性、耐药性、适应性、免疫逃逸，广谱中和抗体产生机制和疫苗等研究领域均做出重要贡献。已发表学术论文200余篇，在Cell、Nature、Science等世界顶级杂志发表论文14篇；应邀综述和专著章节14篇。截止目前，发表文章经谷歌学者数据库检索已被引用>32000次，谷歌学者H因子为83。承担及参与过多项美国NIH/NIAID艾滋病研究项目，获批总科研经费超过2100万美元。在国内承担国家自然科学基金外国资深学者研究基金团队项目1项、国家自然科学基金面上项目2项、“十三五”重大科技专项子课题1项、“十四五”重点研发计划子课题1项，获批总科研经费超过1200万元。获授权美国发明专利6项和中国发明专利3项。曾多次应邀在国际会议做邀请报告，主办或协助举办国际艾滋病会议。
1978.09-1984.07 哈尔滨医科大学（医学学士）
1984.09-1987.12 中国预防医学科学院（医学硕士）
1998.07-2001.09 美国阿拉巴马大学伯明翰分校（研究助理教授）
1999.06-2001.09 美国阿拉巴马大学伯明翰分校艾滋病中心（副科学家）
2001.10-2006.09 美国杜克大学（研究副教授）
2006.10-2009.08 美国杜克大学（副教授）
2009.10-2020.09 美国杜克大学（教授）
2011.12-现在 吉林大学（教授）
2020.10-现在 美国杜克大学（荣誉教授）
2020.10-现在 太阳城集团（教授）
1. Xiaoqian Xin, Yifeng Liu, Lei Guo, Hui Wang, Daiqiang Lu, Yaotian Chang, Mingming Wan, Yong Zhang, Yaming Shan, Qiao Zhang, Xiaowen Liu*, and Feng Gao*. Improvement of B cell responses by an HIV-1 amphiphilic polymer nanovaccine. Nano Letters. 2023 May 10;23(9):4090-4094. PMID: 37120753(*Co-corresponding authors)
2. Hui Wang, Yuqi Liu, Peng Li, Chaowu Liu, Kuibiao Li, Lan Cao, Ying Zhang, Zichun Cheng, Kailing Huang, Zhouxia Zheng, Xiaoqian Xin, Yifeng Liu, Xiaofang Peng, Dan Liang, Bixia Ke, Tao Wang, Qingpei Chen, Weihua Luo, Chaolang Qin, Lihong Sun, Guobing Chen, Oscar Junhong Luo, Jixi Li, Qiao Zhang, Biao Di, Zhoubin Zhang*, Changwen Ke*, Hongling Jia* and Feng Gao*. Emergence of epidemic variants of SARS-CoV-2 by acquiring combinations of new highly mutable nucleotides in its genome. Journal of Infection. 2023 Jun;86(6):588-592. PMID: 36889511(*Co-corresponding authors)
3. Hongling Jia, Hui Wang, Lan Cao, Zhisheng Lai, Zichun Cheng, Qingpei Chen, Tongzheng Liu, Xiangyi Liu, Yanting Wen, Conghui Xu, Weizhi Lu, Guang Yang, Deqian Zhou, Biao Di*, Feng Gao*, Zhicong Yang*. Genetic analysis of a SARS-CoV-2 Omicron variant from a Chinese traveller returning from overseas. Emerg Microbes Infect. 2022 Dec;11(1):306-309. (*Co-corresponding authors) PMCID: PMC8820795
4. Nan Gao, Yanxin Gai, Lina Meng, Chu Wang, Wei Wang, Xiaojun Li, Tiejun Gu , Mark K Loude , Nicole A Doria-Rose, Kevin Wiehe, Alexandra F Nazzari, Adam S Olia, Jason Gorman, Reda Rawi, Wenmin Wu, Clayton Smith, Htet Khant, Natalia de Val, Bin Yu, Junhong Luo, Haitao Niu, Yaroslav Tsybovsky, Huaxin Liao, Thomas B Kepler, Peter D Kwong, John R Mascola, Chuan Qin*, Tongqing Zhou*, Xianghui Yu*, Feng Gao*. Development of Neutralization Breadth against Diverse HIV-1 by Increasing Ab-Ag Interface on V2. Adv Sci. 2022 Mar 23;e2200063. (*Co-corresponding authors) PMID: 35319830
5. Bhavna Hora, Naila Gulzar, Yue Chen, Konstantinos Karagiannis, Fangping Cai, Chang Su, Krista Smith, Vahan Simonyan, Sharaf Ali Shah, Manzoor Ahmed, Ana M. Sanchez, Mars Stone, Myron S. Cohen, Thomas N. Denny, Raja Mazumder, Feng Gao. Streamlined Subpopulation, Subtype, and Recombination Analysis of HIV-1 Half-Genome Sequences Generated by High-Throughput Sequencing. mSphere. 2020 5(5): e00551-20. PMCID: PMC7565892
6. Xiaojun Li, Elena E. Giorgi, Manukumar Honnayakanahalli Marichann, Brian Foley, Chuan Xiao, Xiang-Peng Kong, Yue Chen, Bette Korber and Feng Gao. Emergence of SARS-CoV-2 through Recombination and Strong Purifying Selection. Science Advances. 2020 6(27): eabb9153.
7. Xiao C, Li X, Liu S, Sang Y, Gao SJ, Gao F. HIV-1 did not contribute to the 2019-nCoV genome. Emerg Microbes Infect. 2020 9(1):378-381. (*Co-corresponding authors) PMID: 32056509
8. Gao N, Gai Y, Meng L, Wang C, Zhang X, Wang W, Qin C, Yu X*, Gao F*. Development of Antibodies with Broad Neutralization Specificities against HIV-1 after Long Term SHIV Infection in Macaques. Viruses. 2020 12(2):163. (*Co-corresponding authors) PMID: 32023860 PMCID: PMC7077270
9. Blasi M, Stadtler H, Chang J, Hemmersbach-Miller M, Wyatt C, Klotman P, Gao F, Wolfe C, Klotman M. Detection of Donor's HIV Strain in HIV-Positive Kidney-Transplant Recipient. N Engl J Med. 2020. 382(2):195-197. PMID: 31914248
10. Song H, Giorgi EE, Ganusov VV, Cai F, Athreya G, Yoon H, Carja O, Hora B, Hraber P, Romero-Severson E, Jiang C, Li X, Wang S, Li H, Salazar-Gonzalez JF, Salazar MG, Goonetilleke N, Keele BF, Montefiori DC, Cohen MS, Shaw GM, Hahn BH, McMichael AJ, Haynes BF, Korber B, Bhattacharya T, Gao F. Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection. Nat Commun. 9(1):1928. 2018. PMID: 29765018; PMC5954121.
11. Bonsignori M, Chen L, Zhou T, Gao F, Sheng Z, Joyce GM, Ozorowski G, Schramm C, Wiehe K, Alam MS, Bradley T, Hwang KK, Luo K, Lu X, Mangiapani M, Iyengar S, Gladden M, Kumar A, Song H, Parks RJ, Acharya P, Bailer RT, Cao A, Chuang GY, Druz A, Georgiev IS, Louder MK, Wu X, Zhang B, Zheng A, Montefiori DC, Michael A. Moody MA, Shaw GM, Hahn BH, Kelsoe G, Hraber P, Korber BT, Boyd S, Fire AZ, Kepler TB, Mascola JR, Shapiro L, Ward A, Liao HX, Kwong PD, Haynes BF. Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimicking Antibody. Cell. 165(2):449-63, 2016. PMID: 26949186
12. Moody MA*, Gao F*, Gurley TC, Amos JD, Kumar A, Hora B, Marshall DJ, Whitesides JF, Xia SM, Parks R, Lloyd KE, Hwang KK, Lu X, Bonsignori M, Finzi A, Vandergrift NA, Alam SM, Ferrari G, Shen X, Tomaras GD, Kamanga G, Cohen MS, Sam NE, Kapiga S, Gray ES, Tumba NL, Morris L, Zolla-Pazner S, Gorny MK, Mascola JR, Hahn BH, Shaw GM, Sodroski JG, Liao HX, Montefiori DC, Hraber PT, Korber BT, Haynes BF*. Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses. Cell Host Microbe. 18(3):354-62. 2015. (*Co-corresponding authors) PMID: 26355218; PMCID: PMC4567706
13. Williams WB, Liao HX, Moody MA, Kepler TB, Alam SM, Gao F, Wiehe K, Trama AM, Jones K, Zhang R, Song H, Marshall DJ, Whitesides JF, Sawatzki K, Hua A, Liu P, Tay MZ, Seaton KE, Shen X, Foulger A, Lloyd KE, Parks R, Pollara J, Ferrari G, Yu JS, Vandergrift N, Montefiori DC, Sobieszczyk ME, Hammer S, Karuna S, Gilbert P, Grove D, Grunenberg N, McElrath MJ, Mascola JR, Koup RA, Corey L, Nabel GJ, Morgan C, Churchyard G, Maenza J, Keefer M, Graham BS, Baden LR, Tomaras GD, Haynes BF. HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies. Science. 349(6249):aab1253. 2015. PMID: 26229114; PMCID: PMC4562404
14. Gao F*, Bonsignori M, Liao HX, Kumar A, Xia SM, Lu X, Cai F, Hwang KK, Song H, Zhou T, Lynch RM, Alam SM, Moody MA, Ferrari G, Berrong M, Kelsoe G, Shaw GM, Hahn BH, Montefiori DC, Kamanga G, Cohen MS, Hraber P, Kwong PD, Korber BT, Mascola JR, Kepler TB, Haynes BF*. Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies. Cell. 158(3):481-91. 2014. (*Co-corresponding authors) PMID: 25065977; PMCID: PMC4150607
15. Liao HX*, Lynch R*, Zhou T*, Gao F*, Alam SM, Boyd SD, Fire AZ, Roskin KM, Schramm CA, Zhang Z, Zhu J, Shapiro L; NISC Comparative Sequencing Program, Becker J, Benjamin B, Blakesley R, Bouffard G, Brooks S, Coleman H, Dekhtyar M, Gregory M, Guan X, Gupta J, Han J, Hargrove A, Ho SL, Johnson T, Legaspi R, Lovett S, Maduro Q, Masiello C, Maskeri B, McDowell J, Montemayor C, Mullikin J, Park M, Riebow N, Schandler K, Schmidt B, Sison C, Stantripop M, Thomas J, Thomas P, Vemulapalli M, Young A, Mullikin JC, Gnanakaran S, Hraber P, Wiehe K, Kelsoe G, Yang G, Xia SM, Montefiori DC, Parks R, Lloyd KE, Scearce RM, Soderberg KA, Cohen M, Kamanga G, Louder MK, Tran LM, Chen Y, Cai F, Chen S, Moquin S, Du X, Joyce MG, Srivatsan S, Zhang B, Zheng A, Shaw GM, Hahn BH, Kepler TB, Korber BT, Kwong PD, Mascola JR, Haynes BF. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature. 496:469-76. 2013. (*Equal contribution) PMID: 23552890; PMCID: PMC3637846
16. Keele BF, Giorgi EE, Salazar-Gonzalez JF, Decker JM, Pham KT, Salazar MG, Sun C, Grayson T, Wang S, Li H, Wei X, Jiang C, Kirchherr JL, Gao F, Anderson JA, Ping LH, Swanstrom R, Tomaras GD, Blattner WA, Goepfert PA, Kilby JM, Saag MS, Delwart EL, Busch MP, Cohen MS, Montefiori DC, Haynes BF, Gaschen B, Athreya GS, Lee HY, Wood N, Seoighe C, Perelson AS, Bhattacharya T, Korber BT, Hahn BH, Shaw GM. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc Natl Acad Sci U S A. 105:7552-7. 2008. PMID: 18490657; PMCID: PMC2387184
17. Cai F, Chen H, Hicks CB, Bartlett JA, Zhu J and Gao F. Detection of minor drug-resistance populations by parallel allele-specific sequencing. Nat. Methods. 4:123-125. 2007. PMID: 17206150; PubMed PMID: 17206150
18. Weaver EA, Lu Z, Camacho ZT, Moukdar F, Liao H-X, Ma B-J, Muldoon M, Theiler J, Nabel GJ, Letvin NL, Korber BT, Hahn BH, Haynes BF and Gao F. Cross-subtype T Cell Immune Responses induced by an HIV-1 Group M Consensus Env Immunogen. J. Virol. 80:6745-6756. 2006. PMID: 16809280; PMCID: PMC1489064
19. Switzer WM, Salemi M, Shanmugam V, Gao F, Cong ME, Kuiken C, Bhullar V, Beer BE, Vallet D, Gautier-Hion A, Tooze Z, Villinger F, Holmes EC and Heneine W. Ancient co-speciation of simian foamy viruses and primates. Nature 17;434(7031):376-80. 2005. PMID: 15772660
20. Bailes E, Gao F, Bibollet-Ruche F, Courgnaud V, Peeters M, Marx PA, Hahn BH, Sharp PM. Hybrid origin of SIV in chimpanzees. Science 300:1713, 2003. PMID: 12805540
21. Gao F, Bhattacharya T, Gaschen, B, Taylor J, Moore JP, Novitsky V, Yusim K, Lang D, Foley B, Beddows S, Alam M, Haynes B, Hahn BH, and Korber B. Consensus and Ancestral State HIV Vaccines (Letter). Science 299:1517-1518. 2003.
22. Gaschen B, Taylor J, Yusim K, Foley B, Gao F, Lang D, Novitsky V, Haynes B, Hahn BH, Bhattacharya T, Korber B. Diversity considerations in HIV-1 vaccine selection. Science 296:2354-60, 2002. PMID: 12089434
23. Santiago M, Rodenburg C, Kamenya S, Bibollet-Ruche F, Gao F, Bailes E, Meleth S, Soong S, Kilby J, Moldoveanu Z, Fahey B, Muller M, Ayouba A, Nerrienet E, McClure H, Heeney J, Pusey A, Collins A, Boesch C, Wrangham R, Goodall J, Sharp P, Shaw GM and Hahn BH. SIVcpz in wild chimpanzees. Science, 295:465, 2002. PMID: 11799233
24. Korber B, Bhattacharya T, Theiler J, Gupta R, Lapedes A, Hahn BH, Gao F, Muldoon M, Wolinsky S. Search for the Origin of HIV and AIDS. Science 289: 1140-1141, 2000.
25. Korber B, Muldoon M, Theiler J, Gao F, Gupta R, Lapedes A, Hahn BH, Wolinsky S and Bhattacharya T. Timing the ancestor of the HIV-1 Pandemic strains. Science 288:1789-1796, 2000. PMID: 10846155
26. Robertson DL, Anderson J, Bradac JA, Carr JK, Foley B, Gao F, Hahn BH, Kuiken C, Learn GH, Leitner T, McCutchan F, Osmanov S, Peeters M, Pieniaze D, Salminen M, Wolinsky S, and Korber B. HIV-1 Nomenclature Proposal. Science 288:55, 2000. PMID: 10766634
27. Gao F, Bailes E, Robertson DL, Chen Y, Rodenburg CM, Michael SF, Cummins LB, Arthur LO, Peeters M, Shaw GM, Sharp PM and Hahn BH. Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes. Nature 397:436-441, 1999. PMID: 9989410
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1. 高峰，第五章-HIV2及SIV的病毒学及生物学，《艾滋病毒感染与艾滋病》，人民卫生出版社，68页-88页，1999年。
2. 高峰，第二章-HIV感染的分子流行病学，《艾滋病毒感染与艾滋病》，人民卫生出版社，13页-32页，1999年。
1.入选国家第十六批海外引才计划创新人才长期项目
2.入选2019年“珠江人才计划”杰出人才项目
专业委员：
中国医疗保健国际交流促进会分子诊断学分会 副主任委员 2022-8-27
中国实验动物学会免疫与细胞治疗专业委员会 副主任委员 2018-12-09
中国性病艾滋病防治协会艾滋病病毒专业委员会 副主任委员 2020-10-16
中国性病艾滋病防治协会基础研究专业委员会 常务委员 2020-12-16
天津市滨海新区艾滋病疫苗研究会 会长 2020-12-15
专业杂志编委：
One Health Bulletin (Editorial Board) 2021-现在
Animal Models and Experimental Medicine (Editorial Board) 2022-现在
Viruses 2009-现在
中国病毒病杂志 2010-现在
Current HIV Research 2018-现在
PLOS ONE 2019-现在
Zoonotic Diseases 2021-现在
